Ubuhanga bushya bwo kuvura rosacea ukoresheje tekinoroji ya pulse nziza: Muri vivo nubushakashatsi bwamavuriro

Amavu n'amavuko:Rosacea nindwara idakira yuruhu yibasira mumaso, kandi ingaruka zokuvura ntabwo zishimishije. Dushingiye kuri Photomodulation yuburyo bwiza bwa tekinoroji (OPT), twateje imbere uburyo bwo kuvura bushya, aribwo, OPT yateye imbere ifite ingufu nke, impiswi eshatu, nubugari burebure (AOPT-LTL).

Intego:Twari tugamije gushakisha uburyo bushoboka hamwe nuburyo bwimikorere ya molekuline yubuvuzi bwa AOPT-LTL muburyo bwimbeba ya rosacea. Byongeye kandi, twasuzumye umutekano n’ingirakamaro ku barwayi bafite erythematotelangiectatic rosacea (ETR).

Ibikoresho n'uburyo:Isesengura rya Morphologique, histologique, na immunohistochemicals ryakoreshejwe mugushakisha imikorere nuburyo bwo kuvura AOPT-LTL muburyo bwa LL-37 buterwa na rosacea imeze nkimbeba. Byongeye kandi, abarwayi 23 barwaye ETR barimo kandi bahabwa ibihe bitandukanye byo kuvurwa mugihe cyibyumweru 2 bitewe nuburemere bwimiterere yabo. Ingaruka zo kuvura zasuzumwe ugereranya amafoto yubuvuzi kuri baseline, icyumweru 1, n’amezi 3 nyuma yo kuvurwa, uhujwe nagaciro gatukura, GFSS, n amanota ya CEA.

Ibisubizo:Nyuma yo kuvura AOPT-LTL yimbeba, twabonye ko fenotipike imeze nka rosacea, kwinjiza ingirabuzimafatizo, hamwe n’imitsi idasanzwe y’imitsi byahinduwe neza, kandi imvugo ya molekile yibanze ya rosacea yarabujijwe cyane. Mu bushakashatsi bw’ubuvuzi, ubuvuzi bwa AOPT-LTL bwagize ingaruka zishimishije zo kuvura kuri erythma no gutembera kw'abarwayi ba ETR. Nta bintu bikomeye byagaragaye byagaragaye.

Umwanzuro:AOPT-LTL nuburyo bwizewe kandi bwiza bwo kuvura ETR.