Gusaza k'uruhu —— Kwita ku ruhu

Hormone igabanuka uko imyaka igenda ishira, harimo estrogene, testosterone, dehydroepiandrosterone sulfate, na hormone yo gukura. Ingaruka za hormone ku ruhu ni nyinshi, harimo kwiyongera kwa kolagene, kwiyongera k'uruhu, no kunoza uruhu. Muri byo, ingaruka za estrogene ziragaragara cyane, ariko uburyo bwo kugira ingaruka ku ngirabuzimafatizo buracyumvikana neza. Ingaruka ya estrogene ku ruhu igaragarira cyane cyane muri keratinocytes ya epidermis, fibroblast na melanocytes ya dermis, ndetse na selile follicle selile na glande sebaceous. Iyo ubushobozi bwumugore bwo gukora estrogene bugabanutse, gusaza kwuruhu birihuta. Kubura imisemburo estradiol bigabanya ibikorwa byurwego rwibanze rwa epidermis kandi bikagabanya synthesis ya fibre ya kolagen na elastique, byose ni ngombwa kugirango ibungabunge uruhu rwiza. Kugabanuka k'urwego rwa estrogene nyuma yo gucura ntabwo biganisha gusa ku kugabanuka kw'ibigize uruhu rwa kolagene, ahubwo nanone metabolism ya selile dermal igira ingaruka ku gipimo cya estrogene nkeya nyuma yo gucura, kandi izi mpinduka zirashobora guhinduka vuba mugukoresha estrogene. Ubushakashatsi bwemeje ko estrogene y’umugore ishobora kongera kolagene, ikagumana umubyimba w’uruhu, kandi ikagumana ubushuhe bw’uruhu ndetse n’imikorere ya barrière ya stratum corneum yongera aside aside glycosaminoglycans na aside hyaluronic, kugirango uruhu rugumane neza. Birashobora kugaragara ko kugabanuka kwimikorere ya sisitemu ya endocrine yumubiri nabyo ari kimwe mubintu byingenzi bigira uruhare muburyo bwo gusaza kwuruhu.

Kugabanya ururenda ruva muri pitoito, adrenal, na gonad bigira uruhare muguhinduka kuranga umubiri hamwe na fenotype yuruhu hamwe nimyitwarire ijyanye no gusaza. Urwego rwa serumu ya 17β-estradiol, dehydroepiandrosterone, progesterone, imisemburo ikura, hamwe na hormone yo hepfo ya insuline ikura (IGF) -Ndagabanuka uko imyaka igenda ishira. Nyamara, urwego rwimisemburo ikura na IGF-I muri serumu yumugabo rwaragabanutse cyane, kandi kugabanuka kwimisemburo ya hormone mubantu bamwe bishobora kubaho mugihe cyakera. Imisemburo irashobora kugira ingaruka kumiterere yuruhu no mumikorere, uruhu rworoshye, gukira, lipogenezi ya cortical, na metabolism y'uruhu. Ubuvuzi bwa Estrogene bushobora kwirinda gucura no gusaza kwa endogenous.

—— ”Uruhu Epiphysiology” Yinmao Dong, Laiji Ma, Itangazamakuru ry’inganda

Kubwibyo, uko tugenda dukura, ibitekerezo byacu kumiterere yuruhu bigomba kwiyongera buhoro buhoro. Turashobora gukoresha abanyamwugaibikoresho byo gusesengura uruhukwitegereza no guhanura icyiciro cyuruhu, guhanura ibibazo byuruhu hakiri kare, no kubikemura neza.