Nyuma yangiritse cyangwa karandeba kugeza kuri epidermal, uburyo bwo gusana bidatinze uruhu ruzihutisha umusaruro wa Keratinocytes, gabanya igihe cyo gusimbuza ingirabuzimafatizo, kandi karemo umusaruro no kurekura hyperkeratose no gutwika hyperkeratose no gutwika hyperkeratose no gutwika uruhu. Ibi kandi birasanzwe kubimenyetso byumye byurukundo.
Kuvuga ko umuriro waho karashobora kandi kuzamura uruhu, mubyukuri, gusenyuka kwa bariyeri bifasha syntomasi no kurekura crtokiya no kurekura crtokine za pro-infyuma, cyane cyane netrochics, irasenyutse. Nyuma yo gukurura ahagana ahari, nyuma yo kugera aho ujya, Cathepsin G, Cathepsin g, buringaniza mu mpapuro zikikije, kandi zitunganya uburinganire muri Keratinocytes. Ingaruka zishobora gutezimbere cyane: 1. Kwangirika kwa selile; 2. Kurekura Scokine ya Pro-Inflammatory; 3. Kwangirika imburagihe cyo kuvugana na selire kuri-selire uteza imbere selile Mitosis. Igikorwa cya proteolutic gikora ku ruhu rwumye, gishobora kandi kugira ingaruka nziza yunvikana muri epidermis, zifitanye isano na priritus nububabare. Gusaba cyane acide tranexamic na α1-antitrypsin (umunyamurika yoroheje) kuri xerose agira akamaro, ansaba ko xeroderma ifitanye isano nibikorwa bya proteolyct.
Epidermis yumye bivuze koinzitizi y'uruhu irahungabana, lipide irazimiye, poroteyine iragabanuka, hamwe nibintu byo gutahura isuku birasohoka.Kuma ku ruhu byatewe no kwangirika kwa bariyeriitandukanye no gukama byatewe no kugabanya imbaraga za sebum, kandi ingaruka za lipid yoroshye ya lipid akenshi inanirwa guhura nibyopera. Gutongana Amavuta yo kwisiga byateguwe kuba bariyeri ntibigomba gusa ko Stratum yongererana, nka ceramu, ibintu bisanzwe, kandi bigabanya ibice bituzuye bya Keraminocytes. Kuma kuruhu bikunze guherekezwa na Prururus, kandi hiyongereyeho ibikorwa bya Antipruritike bigomba gusuzumwa.
Igihe cya nyuma: Jun-10-2022
