Amavuta yo kwisiga hamwe na Pigment Metabolism

Amavuta yo kwisiga yera kandiPigmentMetabolism

Melanin anabolism igabanijwemo ibihe bitandukanye. Abahanga bemeza ko bishoboka kwiga imiti yera kandi igakora ibihe bitandukanye.

(1) Intangiriro yambere ya synthesis ya melanin

Kubangamira inyandiko mvugo na / cyangwa glycosylation ya tyrosinase; Kubuza abagenzuzi mugushinga tyrosinase; Control Kugenzura nyuma ya transcriptque ya tyrosinase.

(2) Igihe cya Melanin synthesis
Nka enzyme yingenzi na enzyme igabanya igipimo cya synthesis ya melanin, inhibitori ya tyrosinase nicyerekezo nyamukuru cyubushakashatsi nicyerekezo cyiterambere muri iki gihe. Kubera ko ibintu byinshi byera nka fenol na ibikomoka kuri catechol bisa muburyo bwa tirozine na dopa, ibikoresho byera byerekanwe akenshi bishyirwa mubikorwa nkibidahiganwa cyangwa birwanya tirozine.

(3) Icyiciro cya nyuma cya synthesis ya melanin

Kubuza kwimura melanosome; ibintu bifite serine protease yo kubuza, nka rwj-50353, irinde rwose UBV iterwa na epidermal pigmentation; soya ya trypsin inhibitor ifite ingaruka zigaragara zo kwera ariko nta ngaruka igira ku burozi bwa selile pigment; Niacinamide, irashobora kubuza kwanduza melanocytes hagati ya melanocytes na keratinocytes; Dis Dispersion ya Melanin na metabolism, α-hydroxy aside, aside irike yubusa na aside retinoic, itera kuvugurura ingirabuzimafatizo no guteza imbere keratinocytes ya melaninize yo kuyikuramo.

Twabibutsa ko ubushakashatsi nogukoresha ibintu byera bishingiye kuri metabolism ya melanin yavuzwe haruguru ntibikwiriye gukumira no kuvura ibyapa bya senile. Kubera ko uburyo bwo gukora plaque ya senile bufitanye isano no gukora lipofuscine, ibintu bikora antioxydeide bikoreshwa mugutinda no guhindura ibyapa bya senile.